Multi-frequency ultrasonic transducer
Multi-frequency ultrasonic transducer
- Single LDM : 1, 3MHz / 3, 10MHz / 3, 10, 17MHz
- Dual LDM : 1, 3, 10, 17MHz
DDS (Drug Delivery System) Effect
- oscillating cavitation bubble
- induces disordering of the SCLB
- skin permeability ↑
- SCLB : Stratum Corneum Lipid Bilayer
1, 3MHz : Improves the skin delivery ability of drugs or basic cosmetics
HSP (Heat Shock Protein) – Has the effect of restoring damaged protein
- T.A. Mehta et al.
- Euro. J. vascular and endovascular surgery.
- 29(4) p395~402(2005)
- Frequency is increased ⇒ Ultrasonic wavelength is reduced ⇒ Pressure gradient caught by the skin cells is increased ⇒ HSP concentration is increased
- Applying higher frequencies helps in regenerating and restoring skin cells since the HSP concentration is increased.
- Since the size of the skin cell is about 30um, the ultrasonic frequency to form the maximum pressure gradient in the skin cell is about 25 MHz, and the maximum frequency that can realistically use the thickness vibration of piezoelectric ceramics is 17-20 MHz.